Scientific record

Publications

2025
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution
de Faria FW, Riedel N, Bruder J, et al. Nature Communications
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2025
In vivo intratumoral heterogeneity in a dish: scalable forebrain organoid models of embryonal brain tumors for high-throughput personalized drug discovery
Riedel N, Bruder J, et al. Cancer Communications
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2021
Cell-Type-Specific High Throughput Toxicity Testing in Human Midbrain Organoids
Renner H, Bruder J, et al. Frontiers in Molecular Neuroscience
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2021
Combining Automated Organoid Workflows with Artificial Intelligence-Based Analyses: Opportunities to Build a New Generation of Interdisciplinary High-Throughput Screens for Parkinson’s Disease and Beyond
Renner H, Schöler HR, Bruder J. Movement Disorders
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2020
A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids
Renner H, Bruder J, et al. eLife
The foundational description of the automated workflow, and the source of the reproducibility and calcium-activity data shown on this site.
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2013
Derivation and expansion using only small molecules of human neural progenitors for neurodegenerative disease modeling
Reinhardt P, Bruder J, et al. PLOS ONE
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